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Protein clumps affect neural stem cells
Young, resting neural stem cells have large protein clumps often associated with neurodegeneration. As stem cells age, the aggregates inhibit their ability to make new neurons, Stanford researchers say.
Ethics review needed for AI use in health care
In a perspective piece, Stanford researchers discuss the ethical implications of using machine-learning tools in making health care decisions for patients.
Predicting success of lung cancer drug
With the help of a new radioactive tracer, doctors can predict with more than 80 percent accuracy how well a widely-used lung cancer drug will combat tumors, according to researchers at Stanford.
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A Legacy of Innovation
First synthesis of biologically active DNA in test tube
Nobel laureate Arthur Kornberg creates a strand of biologically active DNA, paving the way for studies of genetics.
First adult human heart transplant in the United States
Norman Shumway successfully transplants a heart into 54-year-old steelworker Mike Kasperak, who survives for 14 days.
First expression of a foreign gene implanted in bacteria by recombinant DNA methods
Geneticist Stanely Cohen transfers a foreign gene into bacterial cells, which then express the gene.
First successful human combined heart/lung transplant in the world (fourth attempted worldwide)
Mary Gohlke receives the world's first combined heart and lung transplant in a landmark operation led by surgeon Bruce Reitz.
Isolation of a gene coding for part of the T-cell receptor, a key to the immune system’s function
Immunologist Mark Davis characterizes the T-cell receptor, believed to regulate the body's response to infectious agents and cancerous diseases.
Isolation of pure hematopoietic stem cells from mice
Pathologist Irving Weissman isolates a rare mouse cell, known as the hematopoetic stem cell, which gives rise to all the cells of the blood and immune systems.
First use of gene expression profiling to predict cancer outcomes
Application and expansion of optogenetics, a technique to control brain cell activity with light
Bioengineer Karl Deisseroth and his team develop a technique known as optogenetics that allows them to genetically alter brain cell activity in mice with light.