Jayakumar Rajadas

 

List of Publications (223)

(* = as PI/Co-PI)

223. Optimization of transdermal deferoxamine leads to enhanced efficacy in healing skin wounds  Duscher D, Trotsyuk AA, Maan ZN, Kwon SH, Rodrigues M, Engel Karl, Stern-Buchbinder ZA, Bonham CA, Whittam AJ, Barrera J, Hu MS, Inayathullah M, Rajadas J, Gurtner GC. Journal of Controlled Release, 2019, (Accepted).

222. Pharmacological antagonism of histamine H2R ameliorated L-DOPA induced dyskinesia via normalization of GRK3 and by suppressing Fos B and ERKin PD. Ahmed MR, Jayakumar M, Ahmed MS, Zamaleeva AI, Tao J, Li EH, Job JK, Pittenger C, Ohtsu H, Rajadas J*. Neurobiology of Aging (2019), doi: https://doi.org/10.1016/j.neurobiolaging.2019.06.004.

221. Salivary thiocyanate as a biomarker of Cystic Fibrosis Transmembrane Regulator function. Malkovskiy AV, Yacob AA, Dunn CE, Zirbes JM, Ryan SP, Bollyky PL, Rajadas J, Milla CE. Anal Chem. 2019, 91(12):7929-7934. doi: 10.1021/acs.analchem.9b01800. [Epub ahead of print] PMID: 31117414

220. Adenosine and hyaluronan modulate lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema (CPFE). Collum SD, Molina JG, Hanmandlu A, Bi W, Pedroza M, Mertens TCJ, Wareing N, Wei W, Wilson C, Sun W, Rajadas J, Bollyky PL, Philip KM, Ren D, Thandavarayan RA, Bruckner BA, Xia Y, Blackburn MR, Karmouty-Quintana H. Dis Model Mech. 2019 Apr 29. pii: dmm.038711. doi: 10.1242/dmm.038711. [Epub ahead of print] PMID: 31036697

219. 4-Methylumbelliferyl glucuronide contributes to hyaluronan synthesis inhibition. Nagy N, Gurevich I, Kuipers HF, Ruppert SM, Marshall PL, Xie BJ, Sun W, Malkovskiy AV, Rajadas J, Grandoch M, Fischer JW, Frymoyer AR, Kaber G, Bollyky PL. J Biol Chem. 2019, 294(19):7864-7877. doi: 10.1074/jbc.RA118.006166. PMID: 30914479.

218. Mozafari M, Rajadas J, Kaplan DL.  An introduction to nanoengineered biomaterials. In Nanoengineered Biomaterials for Regenerative Medicine. Elsevier 2019, Chapter-1, Pages 1-11. doi: 10.1016/B978-0-12-813355-2.00001-6

217. Conformational Preferences of Aβ25-35 And Aβ35-25 in Membrane Mimicking Environments. Sambasivam D, Sivanesan S, Sultana S, Rajadas J*. Protein Pept Lett. 2019 Feb 28. doi: 10.2174/0929866526666190228122849. PMID: 30836907

216. Fidgetin-like 2 siRNA Enhances the Wound Healing Capability of a Surfactant Polymer Dressing. ORourke B, Kramer A, Cao L, Inayathullah M, Guzik H, Rajadas J, Nosanchuk J, Sharp D. Advances in Wound Care. 2019, 8(3), 91-100 doi: 10.1089/wound.2018.0827.

215. Anti-Hyperlipidemic Effects of Synthetic Analogs of Nordihydroguaiaretic acid (NDGA) in Dyslipidemic Rats. Singh M, Bittner S, Li Y, Bittner A, Han L, Cortez Y, Inayathullah M, Arif Z, Parthasarathi R, Rajadas J, Shen WJ, Nicolls M, Kraemer F, Azhar S. British Journal of Pharmacology. 2019, Feb;176(3):369-385. doi: 10.1111/bph.14528 PMID: 30374952.

214. Prolonged survival of transplanted stem cells after ischaemic injury via the slow release of pro-survival peptide analogues crosslinked to an injectable collagen matrix. Lee AS, Inayathullah M, Lijkwan M, Zhao X, Sun W, Park S, Hong W, Parekh M, Malkovskiy A, Lau E, Qin X, Pothineni VR, Sanchez-Freire V, Zhang W, Kooreman N, Ebert A, Chan C, Nguyen P, Rajadas J*, Wu JC. Nature Biomedical Engineering, 2018, 2(2) 104-113. doi: 10.1038/s41551-018-0191-4

213. Characterization of brain dysfunction induced by bacterial lipopeptides that alter neuronal activity and network in rodent brains. Kim KM, Zamaleeva A, Lee YW, Ahmed MR, Kim E, Lee HR, Pothineni VR, Tao J, Rhee S, Jayakumar M, Inayathullah M, Sivanesan S, Red-Horse K, Palmer T, Park J, Madison D, Lee HY, Rajadas J*. Journal of Neuroscience, 2018 PMID: 30381406 DOI: 10.1523/JNEUROSCI.0825-17.2018.

212. PEG/Dextran Double Layer Influences Fe Ion Release and Colloidal Stability of Iron Oxide Nanoparticles. Mohammadi MR, Malkovskiy AV, Jothimuthu P, Kim KM, Parekh M, Inayathullah M, Zhuge Y, Rajadas J*. Scientific Reports. 2018, 8(1):4286. doi: 10.1038/s41598-018-22644-8. PMID: 29523826

211. In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease. Pothineni VR, Parekh MB, Babar MM, Ambati A, Maguire P, Inayathullah M, Kim K, Tayebi L, Potula HS, Rajadas J*. Drug Design, Development and Therapy 2018, 12, 2915–2921.doi: 10.2147/DDDT.S164966

210. Microhemorrhage-associated tissue iron enhances the risk for Aspergillus fumigatus invasion in a mouse model of airway transplantation. Hsu JL, Manouvakhova OV, Clemons KV, Inayathullah M, Tu AB, Sobel RA, Tian A, Nazik H, Pothineni VR, Pasupneti S, Jiang X, Dhillon GS, Bedi H, Rajadas J, Haas H, Aurelian L, Stevens DA, Nicolls MR. Sci Transl Med.2018, 10(429). doi: 10.1126/scitranslmed.aag2616. PMID: 29467298

209. Cytokines as therapeutic agents and targets in heart disease. Dubnika A, Manoukian MAC, Mohammadi MR, Parekh MB, Gurjarpadhye AA, Inayathullah M, Dubniks V, Lakey JRT, Rajadas J*. Cytokine & Growth Factor Reviews. 2018, 43, 54-68. PMID: 30170892 DOI: 10.1016/j.cytogfr.2018.08.003

208. Possible clues for brain energy translation via endo-lysosomal trafficking of APP-CTFs in Alzheimer’s disease. Sivanesan S, Mundugaru R, Rajadas J*. Oxidative Medicine and Cellular Longevity, 2018 2018 Oct 21;2018:2764831. doi: 10.1155/2018/2764831 PMID: 30420907

207. Microemulsion-based synthesis of a visible-light-responsive Si-doped TiO2 photocatalyst and its photodegradation efficiency potential. Karbasi M, Zarrintaj P, Ghafarinazari A, Saeb MR, Mohammadi MR, Yazdanpanah A, Rajadas J, Mozafari M. Materials Chemistry and Physics, 2018, 220, 374-382. doi: 10.1016/j.matchemphys.2018.08.078

206. Strategies for directing cells into building functional hearts and parts. Jafarkhani M, Salehi Z, Kowsari-Esfahan R, Shokrgozar MA, Rezaa Mohammadi M, Rajadas J, Mozafari M. Biomater Sci. 2018, 6(7):1664-1690. doi: 10.1039/c7bm01176h. PMID: 29767196

205. Deferoxamine Can Prevent Pressure Ulcers and Accelerate Healing in Aged Mice. Bonham CA, Rodrigues M, Galvez M, Trotsyuk A, Stern-Buchbinder Z, Inayathullah M, Rajadas J, Gurtner GC. Wound Repair and Regeneration, 2018.. PMID: 30152571 DOI: 10.1111/wrr.12667

204. Controlled Delivery of a Focal Adhesion Kinase Inhibitor Results in Accelerated Wound Closure with Decreased Scar Formation. Ma K, Kwon SH, Padmanabhan J, Duscher D, Trotsyuk AA, Dong Y, Inayathullah M, Rajadas J, Gurtner GC. Journal of Investigative Dermatology, 2018. PMID: 29775632 DOI: 10.1016/j.jid.2018.04.034

203. In vitro and in vivo metabolite identification of a novel benzimidazole compound ZLN005 by LC-MS/MS. Sun W, Nguyen KD, Fitch WL, Banister SD, Tang H, Zhang X, Yu L, Engleman EG, Rajadas J*. Rapid Commun Mass Spectrom. 2018, 32(6), 480-488. doi: 10.1002/rcm.8060. PMID: 29334584

202. Nordihydroguaiaretic acid, a lignan from Larrea tridentata (Creosote bush) protects against ALIOS diet-induced metabolic dysfunction in mice. Chan JKW, Bittner S, Bittner A, Atwal S, Shen WJ, Inayathullah M, Rajadas J, Nicolls MR, Kraemer FB, Azhar S. Journal of Pharmacology and Experimental Therapeutics. 2018, 365 (2) 281-290. doi: 10.1124/jpet.117.243733

201. Endothelial APLNR regulates tissue fatty acid uptake and is essential for apelin's glucose-lowering effects. Hwangbo C, Wu J, Papangeli I, Adachi T, Sharma B, Park S, Zhao L, Ju H, Go GW, Cui G, Inayathullah M, Job JK, Rajadas J, Kwei SL, Li MO, Morrison AR, Quertermous T, Mani A, Red-Horse K, Chun HJ. Sci Transl Med. 2017 Sep 13;9(407). doi: 10.1126/scitranslmed.aad4000. PMID: 28904225

200. Delivery of monocyte lineage cells in a biomimetic scaffold enhances tissue repair. Hu MS, Walmsley GG, Barnes LA, Weiskopf K, Rennert RC, Duscher D, Januszyk M, Maan ZN, Hong WX, Cheung AT, Leavitt T, Marshall CD, Ransom RC, Malhotra S, Moore AL, Rajadas J, Lorenz HP, Weissman IL, Gurtner GC, Longaker MT. JCI Insight. 2017 Oct 5;2(19). doi: 10.1172/jci.insight.96260. PMID: 28978794

199. Preparation and characterization of cardamom extract-loaded gelatin nanoparticles as effective targeted drug delivery system to treat glioblastoma. Nejat H, Rabiee M, Varshochian R, Tahriri M, Jazayeri HE, Rajadas J, Ye H, Cui Z, Tayebi L. Reactive and Functional Polymers, 2017, 120, 46-56. doi: 10.1016/j.reactfunctpolym.2017.09.008

198. Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis. Collum SD, Chen NY, Hernandez AM, Hanmandlu A, Sweeney H, Mertens TCJ, Weng T, Luo F, Molina JG, Davies J, Horan IP, Morrell NW, Amione-Guerra J, Al-Jabbari O, Youker K, Sun W, Rajadas J, Bollyky PL, Akkanti BH, Jyothula S, Sinha N, Guha A, Karmouty-Quintana H. Br J Pharmacol. 2017 Oct;174(19):3284-3301. doi: 10.1111/bph.13947. PMID: 28688167

197. Nanoparticles hybridization to engineer biomaterials for drug delivery. Mohammadi MR, Sun W, Inayathullah M, Rajadas J*. In: Nanobiomaterials Science, Development and Evaluation. eds: Razavi M, Thakor A. 2017, Ch: 8, p: 147-161. doi: 10.1016/B978-0-08-100963-5.00008-2

196. Nanomaterials Engineering For Drug Delivery: Hybridization Approach. Mohammadi MR, Nojoomi A, Mozafari M, Dubnika A, Inayathullah M, Rajadas J*. J Mater Chem B. 2017, 5, 3995-4018. doi: 10.1039/C6TB03247H

195. Therapeutic Nanoparticles for Targeted Delivery of Anticancer Drugs. Alasvand N, Urbanska AM, Rahmati M, Saeidifar M, Gungor-Ozkerim PS, Sefat F, Rajadas J, Mozafari M. In Multifunctional Systems for Combined Delivery, Biosensing and Diagnostics, 2017, 245-259. doi: 10.1016/B978-0-323-52725-5.00013-7

194. Discovery of novel brain permeable and G protein-biased beta-1 adrenergic receptor partial agonists for the treatment of neurocognitive disorders. Yi B, Jahangir A, Evans AK, Briggs D, Ravina K, Ernest J, Farimani AB, Sun W, Rajadas J, Green M, Feinberg EN, Pande VS, Shamloo M. PLoS One. 2017, 12(7):e0180319. PMID: 28746336 doi: 10.1371/journal.pone.0180319.

193. Pharmacological rescue of diabetic skeletal stem cell niches. Tevlin R, Seo EY, Marecic O, McArdle A, Tong X, Zimdahl B, Malkovskiy A, Sinha R, Gulati G, Li X, Wearda T, Morganti R, Lopez M, Ransom RC, Duldulao CR, Rodrigues M, Nguyen A, Januszyk M, Maan Z, Paik K, Yapa KS, Rajadas J, Wan DC, Gurtner GC, Snyder M, Beachy PA, Yang F, Goodman SB, Weissman IL, Chan CK, Longaker MT. Science Translational Medicine. 2017, 9 (372), eaag2809. PMID: 28077677 DOI: 10.1126/scitranslmed.aag2809

192. Screening of NCI DTP library to identify new drug candidates for Borrelia burgdorferi. Pothineni VR, Wagh D, Babar MM, Inayathullah M, Watts RE, Kim KM, Solow-Cordero D, Tayebi L, Gurjarpadhye AA, Parekh MB, Rajadas J*. J Antibiotics 2017, 70(3), 308-312. doi: 10.1038/ja.2016.131. PMID: 27826144.

191. Pharmaceuticals and Stem Cells in Autism Spectrum Disorders: Wishful Thinking? Sivanesan S, Tan A, Jeyaraj R, Lam J, Gole M, Hardan A, Ashkan K, Rajadas J*, World Neurosurgery 2017, 98: 659–672. PMID: 27725300 doi:.10.1016/j.wneu.2016.09.100

190. From Solvent-Free Microspheres to Bioactive Gradient Scaffolds. Rasoulianboroujeni M, Yazdimamaghani M, Khoshkenar P, Pothineni VR, Kim KM, Murray TA, Rajadas J, Mills DK, Vashaee D, Moharamzadeh K, Tayebi L. Nanomedicine. 2017;13(3):1157-1169. doi: 10.1016/j.nano.2016.10.008. PMID: 27793788

189. Sutureless microvascular anastomosis with the aid of heparin loaded poloxamer 407. Özer F, Nişancı M, Taş Ç, Rajadas J, Alhan D, Bozkurt Y, Günal A, Demirtaş S, Işık S. Journal of Plastic, Reconstructive & Aesthetic Surgery. 2017, 70(2):267-273. PMID: 27939908 DOI: 10.1016/j.bjps.2016.10.012.

188. Dynamic CT imaging of volumetric changes in pulmonary nodules correlates with physical measurements of stiffness. Lartey FM, Rafat M, Negahdar M, Malkovskiy AV, Dong X, Sun X, Li M, Doyle T, Rajadas J, Graves EE, Loo BW, Maxim, PG. Radiotherapy and oncology. 2017, 122(2) 313-318. PMID: 27989402 DOI: 10.1016/j.radonc.2016.11.019.

187. ET Goh, G Kirby, R Jayakumar, XJ Liang, A Tan. Chapter 23 – Accelerated Wound Healing Using Nanoparticles. In: Nanoscience in Dermatology. MR Hamblin, P Avci, T Prow Eds. Elsevier/Academic Press. 2016, 287-306. doi: 10.1016/B978-0-12-802926-8.00023-9

186. Attenuation of synaptic toxicity and MARK4/PAR1-mediated Tau phosphorylation by methylene blue for Alzheimer's disease treatment. Sun W, Lee S, Huang X, Liu S, Inayathullah M, Kim KM, Tang H, Ashford JW, Rajadas J*. Scientific Reports 2016, 6, 34784 doi:10.1038/srep34784. PMID: 27708431.

185. Enhanced electrochemical sensing with carbon nanotubes modified with bismuth and magnetic nanoparticles in a lab-on-a-chip (Ferrochip). Jothimuthu P, Hsu JL, Chen R, Inayathullah M, Pothineni VR, Jan A, Gurtner GC, Rajadas J*, Nicolls MR. ChemNanoMat. 2016, 2, 904-910. PMID: 27857882 doi: 10.1002/cnma.201600174. Cover Page: Back Cover, ChemNanoMat 9/2016, page 921.

184. A small molecule TrkB/TrkC neurotrophin receptor co-activator with distinctive effects on neuronal survival and process outgrowth. Yang T, Massa SM, Tran KC, Simmons DA, Rajadas J, Zeng AY, Jang T, Carsanaro S, Longo FM. Neuropharmacology. 2016;110(Pt A): 343-361. doi: 10.1016/j.neuropharm.2016.06.015. PMID: 27334657

183. Identification of new drug candidates against Borrelia burgdorferi using high-throughput screening. Pothineni VR, Wagh D, Babar MM, Inayathullah M, Solow-Cordero D, Kim KM, Samineni A, Parekh M, Tayebi L, Rajadas J*. Drug Design, Development and Therapy. 2016, 10, 1307–1322. PMID: 27103785. doi:10.2147/DDDT.S101486

182. Self-assembly and sequence length dependence on nanofibrils of polyglutamine peptides. Inayathullah M, Tan A, Jeyaraj R, Lam J, Cho NJ, Liu CW, Manoukian MAC, Ashkan K, Mahmoudi M, Rajadas J*. Neuropeptides. 2016, 57, 71-83. PMID: 26874369. doi:10.1016/j.npep.2016.01.011

181. Conformational dynamics of a hydrophobic prion fragment (113-127) in different pH and osmolyte solutions. Inayathullah M, Rajadas J*. Neuropeptides. 2016, 57, 9-14. PMID: 26919915. doi:10.1016/j.npep.2016.02.004.

180. Effect of osmolytes on the conformation and aggregation of some amyloid peptides: CD spectroscopic data. Inayathullah M, Rajadas J*. Data in Brief. 2016, 7, 1643–1651. doi: 10.1016/j.dib.2016.04.070

179. Adipose-Derived Stem Cell-Seeded Hydrogels Increase Endogenous Progenitor Cell Recruitment and Neovascularization in Wounds. Kosaraju R, Rennert RC, Maan ZN, Duscher D, Barrera J, Whittam AJ, Januszyk M, Rajadas J, Rodrigues M, Gurtner GC. Tissue Engineering Part A. 2016, 22(3-4):295-305. PMID: 26871860 doi:10.1089/ten.TEA.2015.0277.

178. In vitro analysis of Mg scaffolds coated with polymer/hydrogel/ceramic composite layers. Yazdimamaghani M, Razavi M, Vashaee D, Pothineni VR, Assefa S, Köhler GA, Rajadas J, Tayebi L. Surface and Coatings Technology, 2016, 301, 126-132. doi:10.1016/j.surfcoat.2016.01.017

177. Nanotechnology and regenerative therapeutics in plastic surgery: The next frontier. Tan A, Chawla R, G N, Mahdibeiraghdar S, Jeyaraj R, Rajadas J, Hamblin MR, Seifalian AM. J Plast Reconstr Aesthet Surg. 2016, Jan; 69(1):1-13. PMID: 26422652

176. Transdermal Delivery of Functional Collagen Via Polyvinylpyrrolidone Microneedles. Sun W, Inayathullah M, Manoukian MA, Malkovskiy AV, Manickam S, Marinkovich MP, Lane AT, Tayebi L, Seifalian AM, Rajadas J*. Annals of Biomedical Engineering, 2015, 43(12):2978-90. PMID: 26066056

175. Transdermal deferoxamine prevents pressure-induced diabetic ulcers. Duscher D, Neofytou E, Wong VW, Maan ZN, Rennert RC, Inayathullah M, Januszyk M, Rodrigues M, Malkovskiy AV, Whitmore AJ, Walmsley GG, Galvez MG, Whittam AJ, Brownlee M, Rajadas J*, Gurtner GC. Proc Natl Acad Sci U S A. 2015, 112(1):94-99. PMID: 25535360

174. [Pyr1]-Apelin-13 delivery via nano-liposomal encapsulation attenuates pressure overload-induced cardiac dysfunction, Serpooshan V, Sivanesan S, Huang X, Mahmoudi M, Malkovskiy AV, Zhao M, Inayathullah M, Wagh D, Zhang XJ, Metzler S, Bernstein D, Wu JC, Ruiz-Lozano P, Rajadas J*, Biomaterials, 2015, 37:289-98. PMID: 25443792

173. Borreliacidal activity of Borrelia metal transporter A (BmtA) binding small molecules by manganese transport inhibition. Wagh D, Pothineni VR, Inayathullah M, Liu S, Kim KM, Rajadas J*. Drug Design, Development and Therapy. 2015, 9: 805-816. PMID: 25709405

172. A Thermo-sensitive Delivery Platform for Topical Administration of Inflammatory Bowel Disease Therapies. Sinha SR, Nguyen LP, Inayathullah M, Malkovskiy A, Habte F, Rajadas J*, Habtezion A. Gastroenterology. 2015. 149(1):52-55. PMID: 25863215

171. A strategy for analyzing bond strength and interaction kinetics between Pleckstrin homology domain and PI(4, 5)P2 phospholipid using force distance spectroscopy and surface plasmon resonance. Malkovskiy AV, Wagh DA, Longo FM, Rajadas J*. Analyst, 2015, 140(13):4558-65. PMID: 26040325

170. Infrared Imaging Tools for Diagnostic Applications in Dermatology. Gurjarpadhye AA, Parekh MB, Dubnika A, Rajadas J and Inayathullah M. SM J Clin. Med. Imaging. 2015;1(1):1001. PMID: 26691203.

169. Recent developments in diffusion tensor imaging of brain. Parekh MB, Gurjarpadhye AA, Manoukian MAC, Dubnika A, Rajadas J, Inayathullah M. Radiol Open J. 2015; 1(1): 1-12. PMID: 27077135

168. Filamentous Bacteriophage Promote Biofilm Assembly and Function. Secor PR, Sweere JM, Michaels LA, Malkovskiy AV, Lazzareschi D, Katznelson E, Rajadas J, Birnbaum ME, Arrigoni A, Braun KR, Evanko SP, Stevens DA, Kaminsky W, Singh PK, Parks WC, Bollyky PL. Cell Host Microbe. 2015 Nov 11;18(5):549-59. PMID: 26567508

167. In Silico Investigation of FOXM1 Binding and Novel inhibitors in Epithelial Ovarian Cancer. Chen Y, Ruben EA, Rajadas J, Teng NN. Bioorg. Med. Chem. Lett. 2015, 23(15):4576-82. PMID: 26164623.

166. In situ Endothelialization: Bioengineering Considerations to Translation. Pang JH, Farhatnia Y, Godarzi F, Tan A, Rajadas J, Cousins BG, Seifalian AM. Small. 2015, PMID: 26460851.

165. Multilayered Magnetic Gelatin Membrane Scaffolds. Samal S, Goranov V, Dash M, Russo A, Shelyakova T, Graziosi P, Lungaro L, Riminucci A, Uhlarz M, Bañobre-López M, Rivas J, Herrmannsdörfer T, Rajadas J, De Smedt S, Braeckmans K, Kaplan D, Dediu V. ACS Applied Materials & Interfaces, 2015, 7(41):23098-109. PMID: 26451743

164. Vascularisation in regenerative therapeutics and surgery. Jeyaraj R, G N, Kirby G, Rajadas J, Mosahebi A, Seifalian AM, Tan A. Materials Science and Engineering: C, 2015, 54: 225–238. PMID: 26046286.

163. Protein Corona Influences Cell–Biomaterial Interactions in Nanostructured Tissue Engineering Scaffolds. Serpooshan V, Mahmoudi M, Zhao M, Wei K, Sivanesan S, Motamedchaboki K, Malkovskiy AV, Goldstone AB, Cohen JE, Yang PC, Rajadas J, Bernstein D, Woo YJ, Ruiz‐Lozano P. Advanced Functional Materials. 2015. DOI: 10.1002/adfm.201500875

162. Altering the Concentration of Silica Tunes the Functional Properties of Collagen-Silica Composite Scaffolds to Suit Various Clinical Requirements. Perumal S, Ramadass SK, Gopinath A, Madhan B, Shanmugam G, Rajadas J, Mandal AB. Journal of the Mechanical Behavior of Biomedical Materials. 2015. PMID: 25922091

161. Cyclosporine Does Not Prevent Microvascular Loss in Transplantation but Can Synergize With a Neutrophil Elastase Inhibitor, Elafin, to Maintain Graft Perfusion During Acute Rejection. Jiang X, Nguyen TT, Tian W, Sung YK, Yuan K, Qian J, Rajadas J, Sallenave JM, Nickel NP, de Jesus Perez V, Rabinovitch M, Nicolls MR. Am J Transplant. 2015, 15(7):1768-81. PMID: 25727073

160. Tissue engineering vascular grafts a fortiori: looking back and going forward. G N, Tan A, Gundogan B, Farhatnia Y, Nayyer L, Mahdibeiraghdar S, Rajadas J, De Coppi P, Davies AH, Seifalian AM. Expert Opin Biol Ther, 2015; 15(2):231-44. PMID: 25427995

159. Significant degradability enhancement in multilayer coating of polycaprolactone-bioactive glass/gelatin-bioactive glass on magnesium scaffold for tissue engineering applications. Yazdimamaghani M, Razavi M, Vashaee D, Pothineni VR, Rajadas J, Tayebi L. Applied Surface Science, 2015, 338:137-145. doi:10.1016/j.apsusc.2015.02.120

158. Cationic Polymers as Carriers through the Blood-Brain Barrier. Samal SK, Dash M, Dubruel P, Mullen K, Rajadas J. “Cationic Polymers in Regenerative Medicine.” Chapter 20, 2015: 539-556. doi:10.1039/9781782620105-00539

157. Polymeric Nanoparticles to Combat Squamous Cell Carcinomas in Patients with Dystrophic Epidermolysis Bullosa. Manoukian MAC, Ott SV, Rajadas J, Inayathullah M. Recent Pat Nanomed (Curr Namomed), 2014, 4: 15-24. PMID: 25506404

156. A hydrodynamic microchip for formation of continuous cell chains. Khoshmanesh K, Zhang W, Tang SY, Nasabi M, Soffe R, Tovar-Lopez FJ, Rajadas J, Mitchell. Applied Physics Letters, 2014, 104(20), 203701. http://dx.doi.org/10.1063/1.4879457

155. Capillary Force Seeding of Hydrogels for Adipose-Derived Stem Cell Delivery in Wounds. Garg RK, Rennert RC, Duscher D, Sorkin M, Kosaraju R, Auerbach LJ, Lennon J, Chung MT, Paik K, Nimpf J, Rajadas J, Longaker MT, Gurtner GC. Stem Cells Transl Med. 2014 Jul 18. pii: sctm.2014-0007. PMID: 25038246

154. Diabetes impairs the angiogenic potential of adipose derived stem cells by selectively depleting cellular subpopulations. Rennert RC, Sorkin M, Januszyk M, Duscher D, Kosaraju R, Chung MT, Lennon J, Radiya-Dixit A, Raghvendra S, Maan ZN, Hu MS, Rajadas J, Rodrigues M, Gurtner GC. Stem Cell Res Ther. 2014 Jun 18;5(3):79. PMID: 24943716

153. Exosomes as Immunotheranostic Nanoparticles. Natasha G, Gundogan B, Tan A, Farhatnia Y, Wu W, Rajadas J, Seifalian AM. Clin Ther. 2014, PMID: 24863261

152. Use of bio-mimmetic 3D technology in therapeutics for heart disease. Serpooshan V, Zhao M, Metzler S, Weo K, Shah PB, Wang A, Mahmoudi M, Malkovskiy AV, Rajadas J, Butte MJ, Bernstein D, Ruiz-Lozano P. Bioengineered. 2014, Jan 14;5(3). PMID: 24637710

151. Effects of light on metalloporphyrin-treated newborn mice. Wong RJ, Schulz S, Espadas C, Vreman HJ, Rajadas J, Stevenson DK. Acta Paediatr. 2014 May;103(5):474-9. PMID: 24417721

150. Promotion of airway anastomotic microvascular regeneration and alleviation of airway ischemia by deferoxamine nanoparticles. Jiang X, Malkovskiy AV, Tian W, Sung YK, Sun W, Hsu JL, Manickam S, Wagh D, Joubert LM, Semenza GL, Rajadas J*, Nicolls MR. Biomaterials. 2014 Jan;35(2):803-13. PMID: 24161166

149. Solvent Microenvironments and Copper Binding Alters the Conformation and Toxicity of a Prion Fragment. Inayathullah M, Satheeshkumar KS, Malkovskiy AV, Carre AL, Sivanesan S, Hardesty JO, Rajadas J*. PLoS One 2013, 8(12): e85160. PMID: 24386462

148. An anti-CD34 antibody-functionalized clinical-grade POSS-PCU nanocomposite polymer for cardiovascular stent coating applications: a preliminary assessment of endothelial progenitor cell capture and hemocompatibility. Tan A, Goh D, Farhatnia Y, G N, Lim J, Teoh SH, Rajadas J, Alavijeh MS, Seifalian AM. PLoS One. 2013 Oct 8;8(10):e77112. PMID: 24116210

147. The effect of bioengineered acellular collagen patch on cardiac remodeling and ventricular function post myocardial infarction. Serpooshan V, Zhao M, Metzler SA, Wei K, Shah PB, Wang A, Mahmoudi M, Malkovskiy AV, Rajadas J, Butte MJ, Bernstein D, Ruiz-Lozano P. Biomaterials. 2013, 34(36):9048-55. PMID: 23992980.

146. Surface modification of a polyhedral oligomeric silsesquioxane poly(carbonate-urea) urethane (POSS-PCU) nanocomposite polymer as a stent coating for enhanced capture of endothelial progenitor cells. Tan, A., Farhatnia, Y., Goh, D., Natasha, G., de Mel, A., Lim, J., Teoh, S., Malkovskiy, A. V., Chawla, R., Rajadas, J., Cousins, B. G., Hamblin, M. R., Alavijeh, M. S., Seifalian, A. M. Biointerphases 2013; 8:22. PMID: 24706135

145. Blocking macrophage leukotriene B4 prevents endothelial injury and reverses pulmonary hypertension. Tian W, Jiang X, Tamosiuniene R, Sung YK, Qian J, Dhillon G, Gera L, Farkas L, Rabinovitch M, Zamanian R, Inayathullah M, Fridlib M, Rajadas J, Peters-Golden M, Voelkel NF, Nicolls MR. Science Trans Med. 2013, 5(200):200ra117. PMID: 23986401.

144. Synthesis of D-amino acid peptides and their effect on beta-amyloid aggregation and toxicity in transgenic Caenorhabditis elegans. Jagota, S., Rajadas, J*. Med Chem Res. 2013; 22 (8): 3991-4000. doi: 10.1007/s00044-012-0386-2

143. Polyvinylpyrrolidone microneedles enable delivery of intact proteins for diagnostic and therapeutic applications. Sun W, Araci Z, Inayathullah M, Manickam S, Zhang X, Bruce MA, Peter Marinkovich M, Lane AT, Milla C, Rajadas J*, Butte MJ. Acta Biomater. 2013, 9(8):7767-74. PMID: 23648574

142. Enhanced Aβ(1-40) production in endothelial cells stimulated with fibrillar Aβ(1-42). Rajadas J*, Sun W, Li H, Inayathullah M, Cereghetti D, Tan A, de Mello Coelho V, Chrest FJ, Kusiak JW, Smith WW, Taub D, Wu JC, Rifkind JM. PLoS One. 2013;8(3):e58194. PMID: 23505467

141. Pathogenesis of Abeta Oligomers in Synaptic Failure. Sivanesan S, Tan A, Rajadas J*. Curr Alzheimer Res. 2013 Mar;10(3):316-23. PMID: 23036017

140. Channelrhodopsins: visual regeneration and neural activation by a light switch. G N, Tan A, Farhatnia Y, Rajadas J, Hamblin MR, Khaw PT, Seifalian AM. New Biotechnol. 2013, 30(5):461-74. PMID: 23664865.

139. Nanotechnology-based gene-eluting stents. Goh D, Tan A, Farhatnia Y, Rajadas J, Alavijeh MS, Seifalian AM. Mol Pharm. 2013 Apr 1;10(4):1279-98. PMID: 23394068

138. Inception to actualization: next generation coronary stent coatings incorporating nanotechnology. Tan A, Farhatnia Y, de Mel A, Rajadas J, Alavijeh MS, Seifalian AM. J Biotechnol. 2013 Mar 10;164(1):151-70. PMID: 23376617

137. Exosomes as nano-theranostic delivery platforms for gene therapy. Tan A, Rajadas J, Seifalian AM. Adv Drug Deliv Rev. 2013 Mar;65(3):357-67. PMID: 22820532

136. Effect of phenolic compounds against A beta aggregation and A beta-induced toxicity in transgenic C. elegans. Jagota, S., and Rajadas, J*. 2012. Neurochemical Research 37:40-48. PMID: 21858698

135. The role of Pro, Gly, Lys, and Arg containing peptides on amyloid-beta aggregation. Jagota, S., and Rajadas, J*. 2012. International Journal of Peptide Research and Therapeutics 18:53-61.

134. Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis. Kurnellas MP, Brownell SE, Su L, Malkovskiy AV, Rajadas J, Dolganov G, Chopra S, Schoolnik GK, Sobel RA, Webster J, Ousman SS, Becker RA, Steinman L, Rothbard JB. J Biol Chem. 2012 Oct 19;287(43):36423-34. PMID: 22955287

133. Biochemical engineering nerve conduits using peptide amphiphiles. Tan A, Rajadas J, Seifalian AM. J Control Release. 2012 Aug 15;163(3):342-352. PMID: 22910143

132. Synergistic photothermal ablative effects of functionalizing carbon nanotubes with a POSS-PCU nanocomposite polymer. Tan A, Madani SY, Rajadas J, Pastorin G, Seifalian AM. J Nanobiotechnology. 2012 Jul 31;10:34. PMID: 22849373

131. Stem cell niches for skin regeneration. Wong VW, Levi B, Rajadas J, Longaker MT, Gurtner GC. Int J Biomater. 2012;2012:926059. PMID: 22701121

130. A critical role for the PAR-1/MARK-tau axis in mediating the toxic effects of Aβ on synapses and dendritic spines. Yu W, Polepalli J, Wagh D, Rajadas J, Malenka R, Lu B. Hum Mol Genet. 2012 Mar 15;21(6):1384-90. PMID: 22156579

129. Glucose Oxidase Incorporated Collagen Matrices for Dermal Wound Repair in Diabetic Rat Models: A Biochemical Study. Arul V, Masilamoni JG, Jesudason EP, Jaji PJ, Inayathullah M, Dicky John DG, Vignesh S, Rajadas J*. J Biomater Appl. 2012 May;26(8):917-38. PMID: 21363874

128. Enhancement of mesenchymal stem cell angiogenic capacity and stemness by a biomimetic hydrogel scaffold. Rustad KC, Wong VW, Sorkin M, Glotzbach JP, Major MR, Rajadas J, Longaker MT, Gurtner GC. Biomaterials.  2012 Jan;33(1):80-90. PMID: 21963148

127. Structural preferences of Aβ fragments in different micellar environments. Sambasivam D, Sivanesan S, Ashok BS, Rajadas J*. Neuropeptides. 2011 Dec;45(6):369-76 . PMID: 22019176

126. Pullulan Hydrogels Improve Mesenchymal Stem Cell Delivery into High-Oxidative-Stress Wounds. Wong VW, Rustad KC, Glotzbach JP, Sorkin M, Inayathullah M, Major MR, Longaker MT, Rajadas J, Gurtner GC. Macromol Biosci. 2011 Nov 10;11(11):1458-66. PMID: 21994074

125. Quantum dots and carbon nanotubes in oncology: a review on emerging theranostic applications in nanomedicine. Tan A, Yildirimer L, Rajadas J, De La Peña H, Pastorin G, Seifalian A. Nanomedicine (Lond). 2011 Aug;6(6):1101-14. PMID: 21955079

124. Vascular anastomosis using controlled phase transitions in poloxamer gels. Chang EI, Galvez MG, Glotzbach JP, Hamou CD, El-Ftesi S, Rappleye CT, Sommer KM, Rajadas J, Abilez OJ, Fuller GG, Longaker MT, Gurtner GC. Nature Medicine. 2011;17(9):1147-52. PMID: 21873986

123. Rationally designed turn promoting mutation in the amyloid-β peptide sequence stabilizes oligomers in solution. Rajadas J, Liu CW, Novick P, Kelley NW, Inayathullah M, Lemieux MC, Pande VS. PLoS One. 2011;6(7):e21776. PMID: 21799748

122. Adipose tissue-derived stem cells display a proangiogenic phenotype on 3D scaffolds. Neofytou EA, Chang E, Patlola B, Joubert LM, Rajadas J, Gambhir SS, Cheng Z, Robbins RC, Beygui RE. J Biomed Mater Res A. 2011;98(3):383-93. PMID: 21630430

121. Efficient gene delivery of primary human cells using peptide linked polyethylenimine polymer hybrid. Dey D, Inayathullah M, Lee AS, LeMieux MC, Zhang X, Wu Y, Nag D, De Almeida PE, Han L, Rajadas J*, Wu JC. Biomaterials. 2011;32(20):4647-58.PMID: 21477858

120. Engineered pullulan-collagen composite dermal hydrogels improve early cutaneous wound healing. Wong VW, Rustad KC, Galvez MG, Neofyotou E, Glotzbach JP, Januszyk M, Major MR, Sorkin M, Longaker MT, Rajadas J, Gurtner GC. Tissue Eng Part A. 2011;17(5-6):631-44. PMID: 20919949

119. A matrix micropatterning platform for cell localization and stem cell fate determination. Huang NF, Patlolla B, Abilez O, Sharma H, Rajadas J, Beygui RE, Zarins CK, Cooke JP. Acta Biomater. 2010;6(12):4614-21. PMID: 20601236

118. Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents. Massa SM, Yang T, Xie Y, Shi J, Bilgen M, Joyce JN, Nehama D, Rajadas J, Longo FM. J Clin Invest. 2010;120(5):1774-85. PMID: 20407211

117. Lipid-Induced Conformational Transition of Amyloid beta Peptide Fragments. Sureshbabu, N., Kirubagaran, R., Thangarajah, H., Malar, E. J., Jayakumar, R*. J Mol Neuroscience. 2010; 41 (3): 368-382. PMID: 20480256

116. Density functional theory analysis and spectral studies on amyloid peptide Abeta(28-35) and its mutants A30G and A30I. Nagarajan S, Rajadas J, Malar EJ. J Struct Biol. 2010;170(3):439-50. PMID: 20188180

115. Interfacial flow processing of collagen. Goffin AJJ, Rajadas J, Fuller GG. Langmuir. 2010 Mar 2;26(5):3514-21. PMID: 20000428

114. Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease. Britschgi M, Olin CE, Johns HT, Takeda-Uchimura Y, LeMieux MC, Rufibach K, Rajadas J, Zhang H, Tomooka B, Robinson WH, Clark CM, Fagan AM, Galasko DR, Holtzman DM, Jutel M, Kaye JA, Lemere CA, Leszek J, Li G, Peskind ER, Quinn JF, Yesavage JA, Ghiso JA, Wyss-Coray T. Proc Natl Acad Sci U S A. 2009;106(29):12145-50.PMID: 19581601

113. Abeta peptide conformation determines uptake and interleukin-1 alpha expression by primary microglial cells. Parvathy S, Rajadas J, Ryan H, Vaziri S, Anderson L, Murphy GM Jr. Neurobiol Aging, 30(11):1792-804, 2009. PMID: 18339452

112. The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in-vitro and in-vivo. Knowles, JK, Rajadas, J., Nguyen, TV, Yang, T., LeMieux, MC, Vander Griend, L., Ishikawa, C., Massa, SM, Wyss-Coray, T., and Longo, FM. J Neurosci, 29(34):10627-37, 2009. PMID: 19710315

111. Conformational polymorphism and cellular toxicity of IAPP and beta AP domains. Andrews, ME, Inayathullah, NM, Rajadas, J* and Malar, EJ. J Struct Biol, 166(2):116-25, 2009. PMID: 19374013

110. Synthesis, pharmacological screening, quantum chemical and in vitro permeability studies of N-Mannich bases of benzimidazoles through bovine cornea. Jesudason EP, Sridhar SK, Malar EJ, Shanmugapandiyan P, Inayathullah M, Arul V, Selvaraj D, Rajadas J*. Eur J Med Chem. 2009 May;44(5):2307-12. PMID: 18486995

109. Surfactant-induced conformational transition of amyloid beta-peptide. Sureshbabu, N., Kirubagaran, R., and Rajadas, J*. Eur Biophys J, 38(4):355-67, 2009.

108. Preparation, physiochemical characterization, and oral immunogenicity of Abeta(1-12), Abeta(29-40), and Abeta(1-42) loaded PLG microparticles formulations. Rajkannan, R., Arul, V., Malar, EJ, and Rajadas, J*. J Pharm Sci, 98(6):2027-39, 2009.

107. Radioprotective effect of dl-alpha-lipoic acid on mice skin fibroblasts. Davis, G.D.J., Masilamoni, J.G., Arul, V., Kumar, M.S.M., Baraneedharan, U., Paul, S.F.D., Sakthivelu, I.V., Jesudason, E.P., and Jayakumar, R*. 2009. Cell Biology and Toxicology 25:331-340.

106. The neuroprotective role of melatonin against amyloid peptide injected mice. Masilamoni, J.G., Jesudason, E.P., Dhandayuthapani, S., Ashok, B.S., Vignesh, S., Jebaraj, W.C.E., Paul, S.F.D., and Jayakumar, R*. 2008. Free Radical Research 42:661-673.

105. Efficacy of DL-alpha lipoic acid against systemic inflammation-induced mice: antioxidant defense system. Jesudason, E.P., Masilamoni, J.G., Jebaraj, C.E., Paul, S.F.D., and Jayakumar, R*. 2008. Molecular and Cellular Biochemistry 313:113-123.

104. Inhibitory effects of short-term administration of DL-alpha-lipoic acid on oxidative vulnerability induced by A beta amyloid fibrils (25-35) in mice. Jesudason, E.P., Masilamoni, J.G., Ashok, B.S., Baben, B., Arul, V., Jesudoss, K.S., Jebaraj, W.C.E., Dhandayuthapani, S., Vignesh, S., and Jayakumar, R*. 2008. Molecular and Cellular Biochemistry 311:145-156.

103. Melatonin prevents amyloid protofibrillar induced oxidative imbalance and biogenic amine catabolism. Gunasingh, M.J., Philip, J.E., Ashok, B.S., Kirubagaran, R., Jebaraj, W.C.E., Davis, G.D.J., Vignesh, S., Dhandayuthapani, S., and Jayakumar, R*. 2008. Life Sciences 83:96-102.

102. Diffusible amyloid oligomers trigger systemic amyloidosis in mice. Senthilkumar, S., Chang, E., and Rajadas, J*. Biochem J,  415(2):207-15, 2008.

101. Aggregation and conformational studies on a pentapeptide derivative. Sambasivam, D., Liu, CW, Jayaraman, M., Malar, EJ, and Rajadas, J*. Biochem Biophys Acta, 1784(11):1659-67, 2008.

100. Lipid-induced conformational transition of the amyloid core fragment Abeta(28-35) and its A30G and A30I mutants. Nagarajan, S., Ramalingam, K., Neelakanta Reddy, P., Cereghetti, DM, Padma Malar, EJ, and Rajadas, J*. FEBS J, 275(10):2415-27, 2008.

99. Amyloid toxicity in skeletal myoblasts: Implications for inclusion-body myositis. Jayaraman, M., Kannayiram, G., and Rajadas, J*. Arch Biochem Biophys, 474(1):15-21, 2008.

98. Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment. Yang, T., Knowles, JK, Lu, Q., Zhang, H., Arancio, O., Moore, LA, Chang, T., Wang, Q., Andreasson, K., Rajadas, J., Fuller, GG, Xie, Y., Massa, SM, and Longo, FM. PLoS ONE, 3(11):e3604, 2008.

97. Anti-inflammatory effect of melatonin on Aβ vaccination in mice. Jesudason, EP, Baben, B., Masilamoni, J., Kirubagaran, R., Jebaraj, WC, and Jayakumar, R*Molecular and Cellular Biochemistry, 298(1-2):69-81, 2007.

96. A therapeutic approach for diabetic wound healing using biotinylated GHK incorporated collagen matrices. Arul, V., Kartha, R., and Jayakumar, R*. 2007. Life Sciences 80:275-284.

95. Lipid Induced β-Amyloid Peptide Assemblage Fragmentation.Widenbrant, MJ, Rajadas, J., Sutardja, C., and Fuller, GG. Biophys J, 91(11):4071-80, 2006.

94. The molecular chaperone a-crystallin protects inflammation-induced neurodegeneration. Masilamoni, JG, Jesudason, EP, Baben B, Jebaraj, CE, Dhandayuthapani, S., and Jayakumar, R*. Biochem Biophys Acta - Molecular Basis of Disease, 2006; 1762: 284 – 293.

93. Lymphocyte toxicity of prion fragments. Murali, J. and Jayakumar, R*. J Biochem, 139(3):329-38, 2006.

92. Characterization of polymeric poly(epsilon-caprolactone) injectable implant delivery system for the controlled delivery of contraceptive steroids. Dhanaraju, MD, Gopinath, D., Ahmed, MR, and Jayakumar, R*., and Vamsadhara, C. J Biomed Mater Res A, 76(1):63-72, 2006.

91. Development of hepatitis B oral vaccine using B-cell epitope loaded PLG microparticles. Rajkannan, R., Dhanaraju, MD, Gopinath, D., Selvaraj, D., and Jayakumar, R*. Vaccine, 24(24):5149-57, 2006.

90. Biodegradation and biocompatibility of contraceptive-steroid-loaded poly (dl-lactide-co-glycolide) injectable microspheres: in vitro and in vivo study. Dhanaraju, MD, Rajkannan, R., Selvaraj, D., Jayakumar, R., and Vamsadhara, C. Contraception, 74(2):148-56, 2006.

89. Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation. Bennett, EJ, Bence, NF, Jayakumar, R., and Kopito, RR. Mol Cell, 17(3):351-65, 2005.

88. Spectroscopic studies on native and protofibrillar insulin. Murali, J. and Jayakumar, R*. J Struct Biol, 150(2):180-9, 2005.

87. The structure of antimicrobial pexiganan peptide in solution probed by Fourier transform infrared absorption, vibrational circular dichroism, and electronic circular dichroism spectroscopy. Shanmugam, G., Polavarapu, PL, Gopinath, D., and Jayakumar, R. Biopolymers, 80(5):636-42, 2005.

86. Red Cell Interactions with Amyloid-b(1-40) fibrils in a Murine Model. Ravi, LB, Poosala, S., Ahn, D., Chrest, FJ, Ingram, D., Spangler, E., Jayakumar, R., Nagababu, E., Mohanty, JG, Talan, M., and Rifkind, JM. Neurobiol Dis, 19(1-2):28-37, 2005.

85. Initial upregulation of growth factors and inflammatory mediators during nerve regeneration in the presence of cell adhesive peptide-incorporated collagen tubes. Ahmed, MR, Basha, SH, Gopinath, D., Muthusamy, R., and Jayakumar, R*. J Peripher Nerv Syst, 10(1):17-30, 2005.

84. Biotinylated GHK peptide incorporated collagenous matrix: A novel biomaterial for dermal wound healing in rats. Arul, V., Gopinath, D., Gomathi, K., and Jayakumar, R*. J Biomed Mater Res B, 73(2):383-91, 2005.

83. Pexiganan-incorporated collagen matrices for infected wound-healing processes in rat. Gopinath, D., Kumar, MS, Selvaraj, D., and Jayakumar, R*. J Biomed Mater Res A, 73(3):320-31, 2005.

82. Isolation and partial characterization of antifungal protein from Bacillus polymyxa strain VLB16. Kavitha S, Senthilkumar S, Gnanamanickam S, Inayathullah M, Jayakumar, R*. Process Biochemistry, 2005, 40(10), 3236-43.

81. Role of fibrillar Ab25-35 in the inflammation induced rat model with respect to oxidative vulnerability. Gunasingh, MJ, Philip, JE, Samuel, JK, Murali, J, Paul, SFD, Jayakumar, R*. Free Radic Res, 39(6):603-12, 2005.

80. The protective effect of a-crystallin against acute inflammation in mice. Masilamoni, JG, Jesudason EP, Bharathi, SN, and Jayakumar, R*. Biochem Biophys Acta, 1740(3):411-20, 2005.

79. Microwave irradiated collagen tubes as a better matrix for peripheral nerve regeneration. Ahmed, MR, Vairamuthu, S., Shafiuzama, M., Basha, SH, and Jayakumar, R*. Brain Res, 1046(1-2):55-67, 2005.

78. The protective role of dl-alpha-lipoic acid in biogenic amines catabolism triggered by Abeta amyloid vaccination in mice. Jesudason, EP, Masilamoni, JG, Kirubagaran, R., Davis, GD, and Jayakumar, R*. Brain Res Bull, 65(4):361-7, 2005.

77. Crystal structure and conformation of N-(t-Butoxycarbonyl)-L-isoleucyl-L-valine methyl ester (Boc-Ile-Val-OMe). Sukumar, N., Sony, S.M.M., Ponnuswamy, M.N., and Jayakumar, R*. 2005. Molecular Crystals and Liquid Crystals 428:77-85.

76. The neuroprotective efficacy of alpha-crystallin against acute inflammation in mice. Masilamoni, J.G., Vignesh, S., Kirubagaran, R., Jesudason, E.P., and Jayakumar, R*. 2005. Brain Research Bulletin 67:235-241.

75. The protective role of DL-alpha-lipoic acid in the oxidative vulnerability triggered by Aß-amyloid vaccination in mice. Jesudason, E.P., Masilamoni, J.G., Jesudoss, K.S., and Jayakumar, R*. 2005. Molecular and Cellular Biochemistry 270:29-37.

74. Peripheral nerve regeneration in cell adhesive peptide incorporated collagen tubes in rat sciatic nerve - early and better functional regain. Ahmed, M.R., and Jayakumar, R*. 2005. Journal of the Peripheral Nervous System 10:390-391.

73. Structure and conformation of N-(t-butoxycarbonyl)-L-isoleucyl-L-leucine methyl ester. Thirumuruhan, R.A., Sony, S.M.M., Shanmugam, G., Ponnuswamy, M.N., and Jayakumar, R*. 2004. Molecular Crystals and Liquid Crystals 414:39-48.

72. Influence of manufacturing parameters on development of contraceptive steroid loaded injectable microspheres. Dhanaraju, M.D., Jayakumar, R*., and Vamsadhara, C. 2004. Chemical & Pharmaceutical Bulletin 52:976-979.

71. Cytotoxic and membrane perturbation effects of a novel amyloid forming model Peptide poly (leucine-glutamic Acid). Jayakumar, R*., Murali, J., Koteeswari, D., and Gomathi, K. J Biochem, 136(4):457-62, 2004.

70. Assemblages of prion fragments: novel model systems for understanding amyloid toxicity. Satheeshkumar, KS, Murali, J., and Jayakumar, R*. J Struct Biol, 148(2):176-93, 2004.

69. Structural analysis of amyloid b peptide fragment (25-35) in different microenvironments. Ganesh, S. and Jayakumar, R*. Biopolymers, 76(5):421-34, 2004.

68. Influence of beta-amyloid fibrils on the interactions between red blood cells and endothelial cells. Ravi, LB, Mohanty, JG, Chrest, FJ, Jayakumar, R*., Nagababu, E., Usatyuk, PV, Natarajan, V., and Rifkind, JM. Neurol Res, 26(5):579-85, 2004.

67. Dermal wound healing processes with curcumin incorporated collagen films. Gopinath, D., Ahmed, MR, Gomathi, K., Chitra, K., Sehgal, PK, and Jayakumar, R* Biomaterials, 25(10):1911-7, 2004.

66. Alpha-crystallin-incorporated collagen matrices as an aid for dermal wound healing. Ahmed, MR, Gopinath, D., Gomathi, K., Sehgal, PK, and Jayakumar, R*. J Biomed Mater Res B Appl Biomater, 69(2):241-8, 2004.

65. Multilayered peptide incorporated collagen tubules for peripheral nerve repair. Ahmed, MR, Venkateshwarlu, U., and Jayakumar, R*. Biomaterials, 25(13):2585-94, 2004.

64. Calix[8]arene mediated self-assembly of tetra peptide H-Leu-Leu-Ile-Leu-OMe. Satheeshkumar, KS, Vasu, G., Visshalakshi, V., Moni, MS, and Jayakumar, R*. J Mol Recognition, 17: 67 – 75, 2004.

63. Presence of pseudo‐peptide bond in the crystal structure of n‐(t‐butoxycarbonyl)‐ε‐n′‐benzyloxycarbony‐l‐lysyl‐l‐isoleucine (boc‐lys (obzl)‐ile). SM Malathy Sony, N Sukumar, MN Ponnuswamy, R Jayakumar. Crystal Research and Technology 39 (4), 368-374, 2004.

62. Peripheral nerve regeneration in RGD peptide incorporated collagen tubes. Rafiuddin Ahmed M, Jayakumar R*. Brain Res. 2003 Dec 12;993(1-2):208-16.

61. Conformational polymorphism of the amyloidogenic peptide homologous to residues 113-127 of the prion protein. Satheeshkumar, KS, and Jayakumar, R*.Biophys J, 85(1):473-83, 2003.

60. Self-assembly of the synthetic polymer (Leu-Glu)I n an amyloid like structure formation. Moses, JP, Satheeshkumar, KS, Murali, J., Alli, D., and Jayakumar, R*. Langmuir, 2003; 19: 3413 - 3418

59. Effect of osmolyte on micellization of SDS at different temperatures. Inayathullah, NM, Jasmine, JG, and Jayakumar, R*. Langmuir, 2003; 19: 9545 - 9547.

58. Red cell perturbations by amyloid beta-protein. Jayakumar, R., Kusiak, JW, Chrest, FJ, Demehin, AA, Murali, J., Wersto, RP, Nagababu, E., Ravi, L., and Rifkind, JM. Biochem Biophys Acta, 1622(1):20-8, 2003.

57. Structural transitions involved in a novel amyloid-like beta-sheet assemblage of tripeptide derivatives. Ganesh, S. and Jayakumar, R*. Biopolymers, 70(3):336-45, 2003.

56. Spectroscopic investigation on gel-forming beta-sheet assemblage of peptide derivatives. Ganesh, S., Prakash, S., and Jayakumar, R*. Biopolymers, 70(3):346-54, 2003.

55. Quercetin incorporated collagen matrices for dermal wound healing processes in rat. Gomathi, K., Gopinath, D., Ahmed, MR, and Jayakumar, R*.Biomaterials, 24(16):2767-72, 2003.

54. Increased neuronal nitric oxide synthase (nNOS) activity triggers picrotoxin-induced seizures in rats and evidence for participation of nNOS mechanism in the action of antiepileptic drugs. Rajasekaran, K., Jayakumar, R., and Venkatachalam, K. Brain Res, 979(1-2):85-97, 2003.

53. Circular dichroism and Fourier transform infrared spectroscopic studies on self-assembly of tetrapeptide derivative in solution and solvated film. Ganesh, S., and Jayakumar, R*. J Pep Res, 61(3):122-8, 2003.

52. Monolayer formation of short helical turn forming peptide derivatives at the air-water and air-solid interface. Ganesh, S., and Jayakumar, R*. Chem Phys Lett, 2003; 380: 681 - 688.

51. Amyloid insulin interaction with erythrocytes. Murali, J., Koteeswari, D., Rifkind, JM, and Jayakumar, R*.Biochem Cell Biol, 81(1):51-9, 2003.

50. Influence of laboratory-ware related changes in conformational and mechanical properties of collagen. Sripriya, R., Ahmed, MR, Sehgal, PK, and Jayakumar, R. J Appl Polym Sci, 87: 2186 – 2192, 2003.

49. Interaction of collagen with corilagin (a hydrolysable tannin). Andrews, ME, Murali, J., Muralidharan, C., Madhulata, W., and Jayakumar, R*. Colloid Polym Sci, 281: 766 – 770, 2003.

48. Preparation and characterization of injectable microspheres of contraceptive hormones. Dhanaraju, MD, Vema, K., Jayakumar, R., and Vamsadhara, C. Int J Pharm, 268(1-2):23-9, 2003.

47. Effect of Ca2+ on the self-assembly of a non-ionic peptide aggregate. Moses, JP, Inayathullah, NM, Murugesan, M., Andrews, ME, Balasubramanian, MP, and Jayakumar, R*. Letters in Peptide Science (International Journal of Peptide Research and Therapeutics), 8: 1025 – 1032, 2003.

46. Electrocatalytic oxidative cleavage by electrogenerated periodate. Khan, F.N., Jayakumar, R., and Pillai, CN. J Mol Catalysis A Chemical, 2003;195 (1-2):139-45.

45. Adiabatic compressibility and intrinsic viscosity studies on peptide aggregates. Andrews, ME, Moses, JP, Sendhil, S., Rakkappan, C., and Jayakumar, R*. Letters in Peptide Science (International Journal of Peptide Research and Therapeutics), 9: 167 – 172, 2002.

44. Sonication-induced sheet formation at the air–water interface. Satheeshkumar, KS, and Jayakumar, R*.Chem Commun, (19):2244-5, 2002.

43. Binding of Hemoglobin to Red Cell Membranes with Eosin-5-maleimide-Labeled Band 3: Analysis of Centrifugation and Fluorescence Lifetime Data. Demehin, AA, Abugo, OO, Jayakumar, R., Lakowicz, JR, and Rifkind, JM. Biochemistry, 41(27):8630-7, 2002.

42. Aging and the Red Cell, Rifkind JM, Abugo OO, Nagababu E, Somasundaram R, Demehin A, Jayakumar R., Editor: Hagen T., Mechanisms of Cardiovascular Aging (Book Chapter). 2002; (11th Ed.): 281-305

41. Study on the stabilization of collagen with vegetable tannin in the presence of acrylic polymer. Madhan, B., Muralidharan, C., and Jayakumar, R*.Biomaterials, 23: 2841 – 2847, 2002.

40. Electrochemical reductive allylation of N-benzylideneethanolamine. Khan, F.N., Jayakumar, R., and Pillai, CN. Tetrahedron letters, 43: 6807 – 6809, 2002.

39. Role of N-t-Boc group in helix initiation in a novel tetrapeptide. Ganesh, S., and Jayakumar, R*.J Pep Res, 59(6):249-56, 2002.

38. Novel Tyrosine derivative to study non-covalent assembly involving C-H-O hydrogen bonding. Satheeshkumar, KS, Padmamalar, EJ, and Jayakumar, R*. Bull Chem Soc Jpn, 75: 89 – 90, 2002.

37. Self-assembly of chromotropic acid – a plausible explanation for monodisperse oligomer formation. Murugesan, M., Rajakumar, VR, Scbibioh, MA, and Jayakumar, R*. Colloid Polym Sci, 280: 1147 – 1150, 2002.

36. High exhaust chrome tanning using fleshing hydrolysate. Kanagaraj J, Samivelu N, Ahmed MR, Jayakumar R. J Am Leather Chem As. 2002; 97:207-214.

35. Improvements In Vegetable Tanning-Can Acrylics Be Co-Tanning Agents. CS Gnanasekaran, B Madhan, R Jayakumar, C Muralidharan. Journal of the American Leather Chemists' Association. 2001: 96 (4), 120-126.

34. Hemodynamic changes during aging associated with cerebral blood flow and impaired cognitive function. Ajmani, RS, Metter, EJ, Jaykumar, R., Igram, DK, Spangler, EL, Abugo, OO, and Rifkind, JM. Neurobiol Aging, 21(2):257-69, 2000.

33. Self-Assembly of a Peptide Boc-(Ile)5-OMe in chloroform and N,N- Dimethylformamide. Jayakumar, R*., Murugesan, M., Asokan, C., and Aulice Scibioh, M. Langmuir, 16: 1489 – 1496, 2000.

32. Aggregational studies on b-turn forming peptide Tyr-Pro-Gly-Asp-Val. Jayakumar, R*., Murugesan, M., Selvi, S., and Aulice Scibioh, M. Langmuir, 16: 3019 – 3021, 2000. 

31. Formation of multilamellar vesicles (“onions”) in peptide based surfactant. Jayakumar, R*., Murugesan, M., and Ahmed, MR. Bioorg Med Chem Lett, 10(14):1547-50, 2000.

30. Anomalous temperature dependence of peptide films at air-water interface. Jayakumar, R*., and Murugesan, M. Bioorg. Med. Chem. Lett, 10(10):1055-7, 2000.

29. Immunological significance of metal induced conformational changes in the mitogenic Achatinin H binding to carbohydrate ligands. Indra, D., Ganesh, S., Ramalingam, K., Asokan, C., and Jayakumar, R. Comp Biochem Physiol C Toxicol Pharmacol, 127(2):177-83, 2000.

28. Structural transitions of non-ionic peptide aggregate in aqueous medium. Murugesan, M., Aulice Scibioh, M., and Jayakumar, R*.Langmuir, 15: 5467 – 5473, 1999.

27. Role of nitric oxide on GABA, glutamic acid, activities of GABA-T and GAD in rat brain cerebral cortex. Jayakumar, AR. Sujatha, R., Paul, V., Asokan, C., Govindasamy, S., and Jayakumar, R*.Brain Res, 837(1-2):229-35, 1999.

26. Involvement of nitric oxide and nitric oxide synthase activity in anticonvulsive action. Jayakumar, AR, Sujatha, R., Paul, V., Puviarasan, K., and Jayakumar, R*.Brain Res Bull, 48(4):387-94, 1999.

25. Behavioural and biochemical changes after simultaneous and post-treatment of vitamin A and D on cadmium toxicity. Sujatha R, Jayakumar AR, Krishnamoorthy MS, Paul V, Jayakumar R. Environ Toxicol Pharmacol. 1999 Jul;7(3):189-97.

24. A novel surface-active peptide derivative exhibits in vitro inhibition of platelet aggregation. Ramesh, CV, Jayakumar, R., and Puvanakrishnan, R. Peptides, 19(10):1695-702, 1998.

23. Self assembling peptides exhibiting antithrombotic activity. Ramesh, CV, Jayakumar, R., and Puvanakrishnan, R. Protein and Peptide Letters, 5: 147 – 154, 1998.

22. 3(10) Helix formation in protected tripeptide. Jayakumar, R*., Aulice Scibioh, M., Vasantha, P., and Manoharan, PT. Protein and Peptide Letters. 5: 321 – 332, 1998.

21. Effect of a novel tetrapeptide derivative in a model of isoproterenol induced myocardial necrosis. Ramesh, CV, Malarvannan, P., Rajadas, J., Jayasundar, S., and Puvanakrishnan, R. Mol Cell Biochem, 187(1-2):173-82, 1998.

20. Aggregation of tetra peptide derivative Boc-Ile-Gly-Met-Thr(OBz)Obz in chloroform. Murugesan, M., Venugopal, M., and Jayakumar, R*.Chem Soc Perkin Trans, 2: 1959 – 1963, 1997.

19. Physiochemical characterization of a novel surfactant peptide containing an arginine cation and laurate anion. Ramesh, CV, Jayakumar, R*., and Puvanakrishnan, R. Colloid & Polymer Science, 275: 1162 – 1168, 1997.

18. Self assembly of non-ionic peptide surfactant in aqueous medium. Murugesan, M., Jayakumar, R*., and Durai, V. Langmuir, 12: 1760 – 1764, 1996.

17. Physico Chemical studies on reverse micelle of sodium Bis(2-ethylhexyl) sulfosuccinate at low water content. Manoj, K.M., Jayakumar, R*., and Rakshith, R. Langmuir, 12: 4068 – 4072, 1996.

16. Surface active peptide-mediated porphyrin aggregation. Venkatesh, B., Jayakumar, R., Pandian, RP, and Manoharan, PT. Biochem Biophys Res Commun, 223(2):390-6, 1996.

15. Synthesis and aggregational behaviour of acidic protenoid. Kumar, ABM, Jayakumar, R., and Panduranga Rao, K. J Polymer Sci, 34: 2915, 1996.

14. Peptide aggregates: a novel model system to study self-assembly of peptides. Jayakumar, R*., Jayanthy, C., and Gomathy, L. Int J Pept Protein Res, 45(2):129-37, 1995.

13. In vitro studies on a novel micelle-forming peptide with anticoagulant activity. Ramesh, CV, Jayakumar, R., and Puvanakrishnan, R. Int J Pept Protein Res, 45(4):386-90, 1995.

12. Aggregation, hydrogen bonding and thermodynamic studies on tetra peptide micelles. Mandal, AB, and Jayakumar, R. J Chem Soc. Faraday Trans, 90: 161-165, 1994.

11. Aggregation, Hydrogen bonding and thermodynamic studies on Boc-Val-Val-Ile-OMe. Jayakumar, R., Jeevan, RG, Mandal, AB, and Manoharan, PT. J Chem Soc Faraday Trans. 90: 2725, 1994.

10. Crystal Structure and Conformation of N-(t-Butoxy Carbonyl)-L-Alanyl-S-Benzyl-L-Cysteine Methyl ester. Sukumar, N., Ponnuswamy, MN, and Jayakumar, R.Bull Chem Soc Jpn, 67: 1976, 1994.

9. Micelle formation of Boc-Val-Val-Ile-OMe: Tripeptide in chloroform and its conformation analysis. Jayakumar, R., Mandal, AB, and Manoharan, PT. J Chem Soc Chem Commun, 853 – 855, 1993.

8. New Micelle forming peptide. Mandal, AB, and Jayakumar, R.J Chem Soc Chem Commun, 237 – 238, 1993.

7. Characterisation of Boc-Lys(Z)-Tyr-NHNH2 Dipeptide-Physico Chemical Studies on the Micelle formation of a dipeptide in the presence and absence of surfactants. Mandal, AB, Dhathathreyan, A., Jayakumar, R., and Ramasami, T. J Chem Soc Faraday Trans, 89: 3075, 1993.

6. Crystal Structure and Conformation of N- (t-butoxy carbonyl)-valine N-Hydroxysuccinimide ester. Sukumar, N., Ponnuswamy, MN, and Jayakumar, R. Bull Chem Soc Jpn, 66: 2101-3, 1993.

5. Crystal Structure and Conformation of N-(t-butoxy carbonyl)-L-isoleucyl-L-alanine benzyl ester. Sukumar, N., Ponnuswamy, MN, and Jayakumar, R. J Cryst Spect Res, 23: 769-72, 1993.

4. Conformational preference of N-Acyl Urea containing valine in DMSO d6. Jayakumar, R* and Pattabhi, V. Bioorg Med Chem Lett, 3: 153 – 156, 1993.

3. Angiotensin I converting enzyme activity in adrinomycin induced nephrosis in rats. Venkatesan, N., Ramesh, CV, Jayakumar, R., and Chandrakasan, G. Toxicology, 85(2-3):137-48, 1993.

2. A Fourier transform infrared spectroscopic investigation of hydrophobic peptides in lipid environment: A monolayer study. Jayakumar, R., Dhathathreyan, A., and Ramasami, T. Ind J Chem, section A: 32:373-375, 1993.

1. C9 conformation of N-(N alpha-[(tert.-butyloxy)-carbonyl]-L-alanyl)-N,N'-dicyclohexylurea in solid and solution. Sudarsanakumar, C., Srinivasan, S., and Jayakumar, R. Int J Pept Protein Res, 39(4):285-90, 1992.