Gene Therapy Clinical Trials
DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem Glioma
This multi-institutional study will prospectively collect tumor and constitutional tissue samples from patients with diffuse brainstem glioma and other types of brainstem gliomas either during therapy or at autopsy to perform an extensive analysis of genetic and molecular abnormalities in these tumors.
Stanford is currently not accepting patients for this trial.
Stanford Investigator(s):
Eligibility
Inclusion Criteria
- Patients of any age with clinical and radiologic diagnosis of diffuse brainstem glioma
- Patients with other high-grade gliomas originating in the brainstem
- Patients with focal gliomas (WHO grade I/II) of the brainstem
- Enrollment in the current version of the St. Jude Tissue Bank protocol for patients
whose tissue samples were obtained at diagnosis and who received treatment at St. Jude
Children's Research Hospital (SJCRH), or correspondent tissue banking consent for
patients treated in other institutions if tissue was obtained prior to death (as
applicable, depending on the standard of each institution)
Exclusion Criteria
- Patients with any type of infiltrative low-grade (WHO grade II) or high-grade glioma
(WHO grade III and IV) originating outside the brainstem
- Patients harboring primary brainstem tumors with other histologic diagnoses (e.g.,
PNET)
Ages Eligible for Study
N/A - 18 Years
Genders Eligible for Study
All
Not currently accepting new patients for this trial
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Michelle Monje
Not Recruiting