Week |
Monday |
Instructor |
Friday |
Instructor |
1 |
3/28 |
Parcels of molecular data in cellular communication: imaging exosome function
C. Contag Lecture notes
Kanada M. Differential fates of biomolecules delivered to target cells via extracellular vesicles. PNAS 2015;112(12):E1433-42.
Kanada M. Signaling by Extracellular Vesicles Advances Cancer Hallmarks.Trends in Cancer. 2016;2(2):84-94.
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4/1 |
Parcels of molecular data in cellular communication: imaging exosome function
C. Contag Lecture notes
|
2 |
4/4 |
Multimodality Imaging of Glutamate for Cancer Diagnosis and Therapy
E. Mittra Lecture notes
Choi C. 2-hydroxyglutarate detection by magnetic resonance spectroscopy in subjects with IDH-mutated gliomas. Nat Med. 2012;18(4):624-30
Hensley C. Glutamine and cancer: cell biology, physiology, and clinical opportunities. J Clin Invest. 2013 Sep;123(9):3678-84.
Keshari K.Hyperpolarized 13C dehydroascorbate as an endogenous redox sensor for in vivo metabolic imagings.PNAS 2011 Nov 15;108(46):18606-11.
Koglin N. Specific PET Imaging of xC- Transporter Activity Using a 18 F-Labeled Glutamate Derivative Reveals a Dominant Pathway in Tumor Metabolism. Clin Cancer Res. 2011 Sep 15;17(18):6000-11.
Takeuchi S. Increased xCT Expression Correlates With Tumor Invasion and Outcome in Patients With Glioblastomas. Neurosurgery. 2013 Jan;72(1):33-41.
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4/8 |
Multimodality Imaging of Glutamate for Cancer Diagnosis and Therapy
E. Mittra Lecture notes
|
3 |
4/11 |
Neural Dynamics and Glymphatics (Stains and Drains in Brains) - Is It All a Wash?
M. Moseley Lecture notes
|
4/15 |
Neural Dynamics and Glymphatics (Stains and Drains in Brains) - Is It All a Wash?
M. Moseley Lecture notes
|
4 |
4/18 |
Imaging agents in robotic surgery
J. Sorger Lecture notes
Hu JC. Temporal trends in radical prostatectomy complications from 1991 to 1998. J Urol. 2003 Apr;169(4):1443-8.
Holland CM. Radical hysterectomy. Best Pract Res Clin Obstet Gynaecol. 2005 Jun;19(3):387-401.
Lanfranco AR. Robotic surgery: a current perspective.Ann Surg. 2004 Jan;239(1):14-21.
Ramirez D. Robotic-assisted laparoscopic prostatectomy: An update on functional and oncologic outcomes, techniques, and advancements in technology. J Surg Oncol. 2015 Dec;112(7):746-52.
Sinha R. Robotic surgery in gynecology. J Minim Access Surg. 2015 Jan-Mar;11(1):50-9.
Daskalaki D.Fluorescence in robotic surgery. J Surg Oncol. 2015 Sep;112(3):250-6.
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4/22 |
Imaging agents in robotic surgery
J. Sorger |
5 |
4/25 |
Image-guided surgery
E. Rosenthal Lecture notes
de Boer E. A standardized light-emitting diode device for photoimmunotherapy. JNM 2014 Nov;55(11):1893-8.
Mitsunaga M. Near-infrared theranostic photoimmunotherapy (PIT): repeated exposure of light enhances the effect of immunoconjugate. Bioconjug Chem. 2012 Mar 21;23(3):604-9.
Sato K.Photoimmunotherapy: comparative effectiveness of two monoclonal antibodies targeting the epidermal growth factor receptor. Mol Oncol. 2014 May;8(3):620-32.
|
4/29 |
Image-guided surgery
E. Rosenthal |
Midterm Exam Materials
Proposal to review
Critique Template
|
6 |
5/2 |
Nanoprobes for diagnosis and imaging
S. Park Lecture notes
James M. A molecular imaging primer: modalities, imaging agents, and applications. Physiol Rev. 2012 Apr;92(2):897-965.
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5/6 |
Nanoprobes for diagnosis and imaging
S. Park |
7 |
5/9 |
Follow that cell! New frontiers in cell tracking
G. Pratx Lecture notes
Kircher MF.Noninvasive cell-tracking methods. Nat Rev Clin Oncol. 2011 Sep 27;8(11):677-88.
Rogers WJ.Technology insight: in vivo cell tracking by use of MRI. Nat Clin Pract Cardiovasc Med. 2006 Oct;3(10):554-62.
Zhang SJ.Comparison of imaging techniques for tracking cardiac stem cell therapy. JNM. 2007 Dec;48(12):1916-9.
|
5/13 |
Follow that cell! New frontiers in cell tracking
G. Pratx |
8 |
5/16 |
Clinical Photoacoustic Imaging: Hype or Hope?
R. Kothapalli Garcia-Uribe A. Dual-Modality Photoacoustic and Ultrasound Imaging System for Noninvasive Sentinel Lymph Node Detection in Patients with Breast Cancer. Sci Rep. 2015 Oct 29;5:15748.
Stoffels I. Metastatic status of sentinel lymph nodes in melanoma determined noninvasively with multispectral optoacoustic imaging. Sci Transl Med. 2015 Dec 9;7(317):317ra199.
Zackrisson S. Light in and sound out: emerging translational strategies for photoacoustic imaging. Cancer Res. 2014 Feb 15;74(4):979-1004.
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5/20 |
Clinical Photoacoustic Imaging: Hype or Hope?
R. Kothapalli |
9 |
5/23 |
Novel PET-MR Imaging Strategies for Studying Living Subjects
F. Chin
Lecture notes
de Galiza Barbosa F.Multi-technique hybrid imaging in PET/CT and PET/MR: what does the future hold? Clin Radiol. 2016 Apr 21. pii: S0009-9260(16)30001-0.
Barthel H. PET/MR in dementia and other neurodegenerative diseases.Semin Nucl Med. 2015 May;45(3):224-33.
Fraum TJ. PET/MRI: Emerging Clinical Applications in Oncology. Acad Radiol. 2016 Feb;23(2):220-36.
Gaertner FC. PET/MR: a paradigm shift. Cancer Imaging. 2013 Feb 27;13:36-52.
Disselhorst JA.Principles of PET/MR Imaging.JNM 2014 May 12;55(Supplement 2):2S-10S.
Queiroz MA. PET/MR in cancers of the head and neck. Semin Nucl Med. 2015 May;45(3):248-65.
Torigian DA. PET/MR imaging: technical aspects and potential clinical applications.Radiology. 2013 Apr;267(1):26-44.
|
5/27 |
Novel PET-MR Imaging Strategies for Studying Living Subjects
F. Chin
Ganji A. Aptamers: new arrows to target dendritic cells. J Drug Target. 2016;24(1):1-12.
Gijs M. Aptamers as radiopharmaceuticals for nuclear imaging and therapy.Nucl Med Biol. 2016 Apr;43(4):253-71.
Oh SS. Synthetic Aptamer-Polymer Hybrid Constructs for Programmed Drug Delivery into Specific Target Cells. J Am Chem Soc. 2014 Oct 22;136(42):15010-5.
Pei X. Clinical applications of nucleic acid aptamers in cancer (Review).Mol Clin Oncol. 2014 May;2(3):341-348.
Sandiford L. The Use of Contrast Agents in Clinical and Preclinical PET-MR Imaging. PET Clin. 2016 Apr;11(2):119-28.
Sun H.Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy. Mol Ther Nucleic Acids. 2014 Aug 5;3:e182.
Wang J. Particle display: a quantitative screening method for generating high-affinity aptamers. Angew Chem Int Ed Engl. 2014 May 5;53(19):4796-801.
Yüce M. Trends in aptamer selection methods and applications. Analyst. 2015 Aug 21;140(16):5379-99.
|
10 |
5/30 |
Holiday |
Final exams June 3-8, 2016 |