Stanford Movement Disorders Center Clinical Trials

PARKINSON’S DISEASE

Neurodegeneration and Brain Function in Aging with HIV and Parkinson's Disease
Sponsor: NIH/NINDS
Site PI: Helen Bronte-Stewart, M.D., M.S.
Study Status: Open, enrollment ongoing
Research coordinator: Varsha Prabhakar
varshap@stanford.edu (650-723-6709)

Frequency Effects of Deep Brain Stimulation on Movement in Parkinson’s Disease.
PI: Helen Bronte Stewart, M.D., M.S.
Study status: Open, enrollment by invitation only
Research coordinator: Chioma Anidi
canidi@stanford.edu (650-723-6709)

The Stanford Parkinson's Disease Plasma Study
Clinical Trials Protocol #: NCT02968433
PI: Helen Bronte-Stewart, M.D., M.S.
Study Status: Open, enrollment ongoing
Research coordinator: Amaris Martinez
amaris94@stanford.edu (650-723-6709)

Pacific Udall Center
Sponsor:
 NIH/NINDS Morris K. Udall Center of Excellence for Parkinson's Disease Research
PI: Tom Montine, MD, PhD
Study status: Open, Enrollment ongoing
Research coordinator: Christine Blabe, MS
udallcenter@stanford.edu
  (650) 721-5351

Healthy Brain Aging Study
Sponsor: NIH/NIA
PI: Victor Henderson, M.D. and Tony Wyss-Coray, Ph.D
Study Status: Open, enrollment ongoing
Research coordinator: Christina Wyss-Coray
ADRCstanford@stanford.edu (650) 721-2409

Development of Multimodal Imaging Biomarkers for Cognitive Dysfunction in Parkinson's Disease
Sponsor: The Michael J. Fox Foundation for Parkinson’s disease Research
PI: Kathleen Poston, M.D., M.S.
Study status: Enrollment closed, study ongoing
Research coordinator: Marian Shahid, MSc
mshahid@stanford.edu (650) 723-0060  

Structural Correlates of Cognitive and Motor Dysfunction in Parkinsonian Disorders
PI: Kathleen Poston, M.D., M.S.
Study Status: Enrollment closed, study ongoing
Research coordinator: Marian Shahid, MSc
mshahid@stanford.edu (650) 723-0060  

Functional Networks in Parkinson's Disease - an fMRI Activation and Functional Connectivity Study
Sponsor: NIH/NINDS
PI: Kathleen Poston, M.D., M.S.
Study Status: Closed to enrollment, analysis ongoing
Research coordinator: Marian Shahid, MSc
mshahid@stanford.edu (650) 723-0060  

A Phase 1/2 Trial Assessing the Safety and Efficacy of Bilateral Intraputaminal and Intranigral Administration of CERE-120 (Adeno-Associated Virus Serotype 2 [AAV2]-Neurturin [NTN]) in Subjects With Idiopathic Parkinson’s Disease
Clinical Trials Protocol #: NCT00400634
Sponsor: Sangamo Biosciences, Inc
Site PI: Kathleen Poston, M.D., M.S.
Study Status: Closed to enrollment, outcome published
Research coordinator: Marian Shahid, MSc
mshahid@stanford.edu (650) 723-0060  

Neural Signatures of Tremor, Bradykinesia and Freezing in the Subthalamic Region in Parkinson’s Disease and their Acute and Long-Term Modulation by Subthalamic Deep Brain Stimulation
Clinical Trials Protocol #: NCT01990313
Sponsor: Medtronic
PI: Helen Bronte Stewart, M.D., M.S.
Study status: Open, enrollment by invitation only
Research coordinator: Chioma Anidi
canidi@stanford.edu (650-723-6709)

Adaptive Closed Loop Neuromodulation and Neural Signatures of Parkinson's Disease (aDBS)
Clinical Trials Protocol #: NCT02384421
Sponsor: Medtronic, Michael  J. Fox Foundation
PI: Helen Bronte Stewart, M.D., M.S.
Study status: Open, enrollment by invitation only
Research coordinator: Chioma Anidi
canidi@stanford.edu (650-723-6709)

Frequency Effects of Deep Brain Stimulation on Movement in Parkinson’s Disease.
PI: Helen Bronte Stewart, M.D., M.S.
Study status: Open, enrollment by invitation only
Research coordinator: Chioma Anidi
canidi@stanford.edu (650-723-6709)

ATYPICAL PARKINSONISM (MSA, PSP, CBD, DLB)

Early Differential Diagnosis of Parkinsonism with Metabolic Imaging and Pattern Analysis 
Sponsor: NIH/NINDS and The Michael J. Fox Foundation for Parkinson’s disease Research
Site PI: Kathleen Poston, M.D., M.S.
Study status: Enrollment Closed, analysis ongoing
Research coordinator: Marian Shahid, MSc
mshahid@stanford.edu (650) 723-0060  

A 12-Week, Multicenter, Randomized, Parallel-Group Study to Assess the Safety, Tolerability, Pharmacokinetics, Biomarker Effects, Efficacy, and Effect on Microglia Activation, as Measured by Positron Emission Tomography, of AZD3241 in Subjects with Multiple System Atrophy
Clinical Trials #: NCT02388295
Sponsor: Astra Zeneca
PI: Kathleen Poston, M.D., M.S.
Study Status: Enrollment Closed, analysis ongoing
Research coordinator: Kara Richardson
kjr9@stanford.edu 650-736-6171

ESSENTIAL TREMOR

Continued Access Protocol: ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential Tremors
Clinical Trials Protocol#: NCT02289560
Sponsor: Insightec
Site PI: Pejman Ghanouni, MD, PhD
Study status: Enrollment Closed, analysis ongoing
Research coordinator: Kathy McDonald
kmcdonal@stanford.edu

Research Programs