Topic List : Developmental Biology
Shorter bones linked to arthritis risk
Humans in Europe and Asia evolved to have shorter bones and an increased risk of osteoarthritis, a trade-off that may have helped them in colder climates, Stanford researchers say.
Ribosomes unexpectedly variable, powerful
Ribosomes, which make proteins, are startlingly variable in their composition and associations. This variability confers on them the ability to regulate genes, confounding previous ideas, Stanford researchers say.
Mouse lemur as model for human disease
Stanford researchers have identified more than 20 mouse lemurs with genetic traits for conditions such as heart disease and eye problems, making the tiny primates potentially useful for understanding diseases in humans.
Pancreatic cells change fate to produce insulin
Alpha cells can convert to insulin-producing beta cells in mice when just two genes are blocked, a new Stanford study shows. A similar mechanism may occur in people with diabetes.
Nusse wins $3 million Breakthrough Prize
The developmental biologist was honored for helping to decode how Wnt signaling proteins affect embryonic development, cancer and the activity of tissue-specific adult stem cells that repair damage after injury or disease.
What microballoons could reveal about gut
A microballoon that fits inside a fruit fly intestine could help scientists understand the forces or nutrients responsible for signaling the intestine to grow or shrink in response to food.
When prions don’t cause mad cow disease
Researchers have found nearly 50 helpful prions in yeast and comparable proteins in humans, suggesting that this dreaded protein type can boost survival and plays a role in evolution.
How Zika affects cranial precursor cells
New research shows that cranial neural crest cells can be infected by the Zika virus, causing them to secrete high levels of cytokines that can affect neurons in the developing brain.
How age affects pancreatic function
A Stanford-led national collaboration to procure and analyze human pancreatic tissue from deceased donors illustrates how the organ’s function changes as we age, and could point the way toward new diabetes treatments.
Variations in regulatory regions predict disease
Researchers have found that analyzing mutations in regions of the genome that control genes can predict medical conditions such as hypertension, narcolepsy and heart problems.