Essential Tremor Research

At Stanford, our physicians are also researchers, always working to find the most effective, least invasive therapies. Browse our most recent publications and research studies, clinical trials, and check out our physicians' research labs. 


Diffusion MRI tractography for improved transcranial MRI-guided focused ultrasound thalamotomy targeting for essential tremor

Authors: Qiyuan Tian, Max Wintermark, W. Jeffrey Elias, Pejman Ghanouni, Casey H. Halpern, Jaimie M. Henderson, Diane S. Huss, Maged Goubran, Christian Thaler, Raag Airan, Michael Zeineh, Kim Butts Pauly, Jennifer A. McNab

Published: May 8, 2018

Neurological adverse event profile of magnetic resonance imaging–guided focused ultrasound thalamotomy for essential tremor

Authors: Paul S. Fishman MD PhD W. Jeffrey Elias MD, Ryder Gwinn MD, Nir Lipsman MD PhD, Michael Schwartz MD, Jim W. Chang MD PhD, Takaomi Taira MD PhD, Vibhor Krishna MD MSci, Ali Rezai MD, Kazumichi Yamada MD PhD, Keiji Igase MD PhD, Rees Cosgrove MD, Haruhiko Kashima MD, Michael G. Kaplitt MD PhD, Travis S. Tierney MD PhD, Howard M. Eisenberg MD

Published: April 27, 2018

A prospective trial of magnetic resonance–guided focused ultrasound thalamotomy for essential tremor: Results at the 2‐year follow‐up

Authors: Jin Woo Chang MD PhD, Chang Kyu Park MD, Nir Lipsman MD PhD, Michael L. Schwartz MD, Pejman Ghanouni MD PhD, Jaimie M. Henderson MD, Ryder Gwinn MD, Jennifer Witt MD, Travis S. Tierney MD PhD, G. Rees Cosgrove MD, Binit B. Shah MD, Keiichi Abe MD, Takaomi Taira MD PhD, Andres M. Lozano MD, Howard M. Eisenberg MD, Paul S. Fishman MD PhD, W. Jeffrey Elias MD

Published: December 19, 2017

Transcranial MRI‐guided high‐intensity focused ultrasound for treatment of essential tremor: A pilot study on the correlation between lesion size, lesion location, thermal dose, and clinical outcome

Authors: Christian Federau MD MS, Maged Goubran PhD, Jarrett Rosenberg PhD, Jaimie Henderson MD, Casey H. Halpern MD, Veronica Santini MD, Max Wintermark MD, Kim Butts Pauly PhD, Pejman Ghanouni PhD

Published: October 27, 2017

Cost-effectiveness of focused ultrasound, radiosurgery, and DBS for essential tremor

Authors: Ravikumar VK, Parker JJ, Hornbeck TS, Santini VE, Pauly KB, Wintermark M, Ghanouni P, Stein SC, Halpern CH

Published: April 3, 2017

Vocal tremor: novel therapeutic target for deep brain stimulation

Authors: Ravijumar VK, Ho AL, Parker JJ, Eickson-DiRenzo E, Halpern CH

Published: October10,  2016

Specialized volumetric thermometry for improved guidance of MRgFUS in brain

Authors: Michael Marx, Pejman Ghanouni, Kim Butts Pauly

Published: October 4, 2016

A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor

Authors: W. Jeffrey Elias, M.D., Nir Lipsman, M.D., Ph.D., William G. Ondo, M.D., Pejman Ghanouni, M.D., Ph.D., Young G. Kim, M.D., Ph.D., Wonhee Lee, M.D., Ph.D., Michael Schwartz, M.D., Kullervo Hynynen, Ph.D., Andres M. Lozano, M.D., Binit B. Shah, M.D., Diane Huss, D.P.T., N.C.S., Robert F. Dallapiazza, M.D., Ph.D., et al. 

Published: August 25, 2016, New England Journal of Medicine

Predicting variation in subject thermal response during transcranial magnetic resonance guided focused ultrasound surgery: Comparison in seventeen subject datasets

Authors: Urvi Vyas, Pejman Ghanouni, Casey H. Halpern, Jeff Elias, Kim Butts Pauly

Pubished: August 24, 2016

Transcranial MRI-guided focused ultrasound: A review of the technologic and neurologic applications

Authors: Pejman Ghanouni, Kim Butts Pauly, W. Jeff Elias, Jaimie Henderson, Jason Sheehan, Stephen Monteith and Max Wintermark

Published: July 2015

Deep brain stimulation for vocal tremor: a comprehensive, multidisciplinary methodology

Authors: Allen L. Ho, MD, Elizabeth Erickson-Direnzo, PhD, Arjun V. Pendharkar, MD, MS, Chih-Kwang Sung, MD, MS, Casey H. Halpern, MD

Published: June 2015