Aging & Geriatrics

A massive study of medical and genetic data shows that people with a particular version of a gene involved in immune response had a lower risk of Alzheimer’s and Parkinson’s disease.

A study in mice finds that white matter — the tissue that transmits messages around the brain — shows the greatest changes as the animals age.

Old muscle stem cells express high levels of the cancer-associated molecule CD47. Blocking a pathway mediated by CD47 restored strength to old mice in a Stanford Medicine study.

Researchers have discovered that a rare mutation inherited with the APOE4 gene variant protects against Alzheimer's, shedding new light on ways to counteract high-risk genes for the disease.

Anne Brunet was awarded the 2022 Lurie Prize in Biomedical Sciences for her efforts to understand the mechanism of aging.

In a Stanford study, sedentary mice appear to benefit from another same-aged mouse’s exercise — if they receive injections of its blood.

The professor of rheumatology and immunology created an early computer database to follow rheumatology patients. The knowledge he gained from it precipitated his “compression of morbidity” hypothesis.

The Food and Drug Administration has approved a new and expensive medication for Alzheimer’s disease, but it’s not clear it helps. Researcher Kevin Schulman discusses what the government should consider before deciding to cover it.

Scientists at Stanford and the Buck Institute have found a way to predict an individual’s immunological decline as well as the likelihood of incurring age-associated diseases and becoming frail.

Scientists have identified a key factor in mental aging and shown that it might be prevented or reversed by fixing a glitch in the immune system’s front-line soldiers.

A single protein is a master regulator of mouse muscle function during aging, a Stanford study finds. Blocking this protein increased muscle strength and endurance in old animals. It may play a role in age-related muscle weakening in humans.